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HaXS8 Size:100nmol Product Name Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Synonyms CAS

SKU: 17877589355

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Description

Product Name Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C83H136N12O23 Molecular Weight 1670

Product Name Azide-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C81H135N13O22 Molecular Weight 1643

and oligonucleotides

17515–17523

Product Name Thalidomide-O-PEG3-C2-Cl Synonyms Thalidomide-4'-O-PEG3-C2-Cl CAS Number n/a Related CAS Molecular Formula C21H25ClN2O8 Molecular Weight 468

HaXS8 Size:100nmol Product Name Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Synonyms CASHaXS8 is a synthetic chemical dimerizer designed to induce covalent and irreversible intracellular dimerization between proteins tagged with HaloTag and SNAP tag. Its a bifunctional molecule featuring a chloroalkane group (specific for HaloTag) and an O6 benzylguanine (BG) derivative (specific for SNAP tag), connected by a flexible polyethylene glycol (PEG) linker. When introduced to cells, HaXS8 bridges HaloTag and SNAP tag fusion proteins by

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