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Fmoc-Val-Cit-PAB amine-amine Contains an E3 ligase ligand

SKU: 79921354479

4.7
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Description

Contains an E3 ligase ligand with alkyl linker and a terminal piperazine moiety

The photostability and brightness of CPY make it a valuable tool for detailed imaging of cellular dynamics

Product Name Thalidomide-5'-O-PEG3-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C21H25N5O8 Molecular Weight 475

Product Name Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C80H111FN12O27 Molecular Weight 1691

616 Purity (HPLC) >= 95% Solubility DMSO

Fmoc-Val-Cit-PAB amine-amine Contains an E3 ligase ligandFmoc Val Cit PAB is a cleavable ADC linker featuring a ValCit dipeptide and a para aminobenzyl (PAB) spacer. The ValCit sequence is selectively cleaved by cathepsin B in lysosomes, while the para aminobenzyl (PAB) spacer supports self immolative release of the attached drug, and the Fmoc protecting group can be removed to enable further functionalization or conjugation. Product Name Fmoc Val Cit PAB Synonyms Fmoc VC PAB OH CAS Number 159858 22 7

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