Make sure you have the correct Energy attached
Blazing Crescendo This one got a ton of hype for being good in Burn lists, which are currently represented in the form of Kuldotha Red lists
Necroface ensures tons of cards are banished, the Nemeses monsters allow you to recycle select banished monsters, and then D.D
I think it would be important to concentrate in the early game to the Erayo/High Noon combo and then use Karn to bring out Mycosynth Lattice(expensive, money wise, but the only way to end the Karn/ML combo is if someone uses Inspiring Statuary to cast Introduction to Annihilation or Scour from Existence) to target Karn
'Phases' in each turn are gone , and while duels follow the same basic format, they are much faster
Assassins Trophy is a truly magical Magic card